Moon Il Kim


Moon II
Postdoctoral Research Scientist
Office: Biotech Building  4121
Telephone: 518-276-4217
Fax: 518-276-2207
E-mail:
Mailing   
Address:
Dept. of Chemical and Biological Engineering
Rensselaer Polytechnic Institute
Center for Biotechnology and Interdisciplinary Studies, Room 4211
110 8th Street
Troy, NY 12180-3590

Background

Postdoctoral Research Scientist (September 2006 ~ Present) in RPI

 

Doctor of Philosophy (September 2002 ~ August 2006)

Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Advisor: Prof. Ho Nam Chang

Dissertational title: Enzyme immobilization and its applications using nanostructured materials

 

Master of Science (March 2001 ~ August 2002)

Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, Advisor: Prof. Ho Nam Chang

Dissertational title: Biological production of succinic acid by Actinobacillus succinogenes sp. 130Z

 

Bachelor of Science (March 1997 ~ February 2001)

Department of Chemical Engineering, Korea Advanced Institute of Science and Technology

 

Research Experience (September 2003 ~ February 2004)

Visiting Scientist at the Environmental Molecular Science Labaratory in Pacific Northwest National Laboratory (Supervisor: Dr. Jungbae Kim)

                                                                                                                                                                                              

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Research area

Recent approaches in nanotechnology have made various nano-structured materials more affordable for a broader range of biocatalytic applications. My research mainly focused on the nano-biotechnology that bridges enzyme engineering, biocatalysis, microarray biochip, material science, cell culture technology, and their multidisciplinary studies.
 
Current research area
 
  • Application of nano-structured materials into biocatalysis
 Enzyme stabilization by CLEA (crosslinked enzyme aggregate) preparation in mesoporous materials
 Surface modification of nanoparticle for enzyme immobilization
 Biocatalysis using enzyme-carbon nanotube conjugates
 
  • High-throughput biocatalysis in microarray biochip
In situ drug metabolite synthesis and in vitro toxicology assay on protein/cell chip
Development of stable enzyme chip without leaching
 
  • Anti-contamination surface design by polymer-enzyme coating
Anti-virus, anti-bacteria, and anti-protein surface design                                                                           

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Publications

  

1. Kim MI, Lee J, Kim J, Jia H, Kwak JH, Dohnalkova A, Hyeon T, Park HG, Chang HN, Wang P, Grate JW (2007) Cross-linked enzyme aggregates in hierarchically-ordered mesoporous silica: a simple and effective method for enzyme stabilization Biotechnol. Bioeng. 96(2), 210.

 

2. Kim MI, Ham HO, Oh SD, Park HG, Chang HN, Choi SH (2006) Immobilization of Mucor javanicus lipase on effectively functionalized silica nanoparticles J. Mol. Catal. B: Enzym. 39, 62.

 

3. Lee J, Kim J, Kim J, Jia H, Kim MI, Kwak JH, Jin S, Dohnalkova A, Park HG, Chang HN, Wang P, Grate JW, Hyeon T (2005) Simple synthesis of hierarchically ordered mesocellular mesoporous silica materials and their successful application to nanoscale enzyme reactors Small 1, 744.

 

4. Oh SD, Byun BS, Lee S, Choi SH, Kim MI, Park HG (2007) Radiolytic Synthesis of Ag-PS Nanoparticles and Their Antimicrobial Efficiency against Staphylococcus aureus and Klebsiella pneumoniase Macromol. Res. (accepted).

 

5. Park SJ, Kim MI, Kim DY, Chang HN, Chang ST (2003) Reverse osmosis treatment of swine wastewater with various pretreatment systems Clean Technology 9(2), 49.

 

6. Kim MI, Kim J, Lee J, Shin S, Na HB, Hyeon T, Park HG, Chang HN (2007) One-dimensional crosslinked enzyme aggregates in SBA-15: superior catalytic behavior to conventional enzyme immobilization submitted to Micropor. Mesopor. Mat.

 

Patent

 

1. Chang HN, Kim DY, Kim MI, Ryu CH, Lee WG (2001) On-site treatment method of food wastes generated from collective residence or institutional food service facilities. Korea Patent, Application number 10-2001-0052629.


                                                                            

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Research Highlights

  
  • Nanobiotechnology
Application of nano-structured materials into biocatalysis
 
  • High-throughput biocatalysis
High-throughput assay for drug metabolite synthesis and toxicology on protein/cell microarray chip
 
  • Anti-contamination surface design
Anti-virus, anti-bacteria, and anti-protein surface development
 
  • Biocatalysis in organic solvent
Dynamic kinetic resolution using biocatalysts and metal catalysts
 
  • Cell culture technology
Mammalian cell culture, microbial high cell density culture

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Honors & Awards

 
Postdoctoral Fellowship Program, KRF (Korea Research Foundation), 2006

                                                                                                                            

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