Akihiro Onishi, Ph.D.
I came from Japan and joined the Dordick lab in 2010.
I am currently a PhD student in the program of Biochemistry and Biophysics.
B.S. in Pharmaceutical Sciences, University of Tokyo (2007)
M.S. in Pharmaceutical Chemistry, University of Tokyo (2009)
I am co-advised by Prof. Jonathan S. Dordick and Prof. Robert J. Linhardt.
My research focuses on the bioengineered heparin.
- U. Bhaskar, G. Li, L. Fu, A. Onishi, M. Suflita, J. S. Dordick, R. J. Linhardt. Combinatorial one-pot chemoenzymatic synthesis of heparin, Carbohydrate Polymers, 122, 399–407, 2015.
- Fu L, Zhang F, Li G, Onishi A, Bhaskar U, Sun P, Linhardt RJ. Structure and activity of a new low-molecular-weight heparin produced by enzymatic ultrafiltration. J Pharm Sci. 2014 May;103(5):1375-83.
- Fu L, Li G, Yang B, Onishi A, Li L, Sun P, Zhang F, Linhardt RJ. Structural characterization of pharmaceutical heparins prepared from different animal tissues. J Pharm Sci. 2013 May;102(5):1447-57.
- Suwan J, Torelli A, Onishi A, Dordick JS, Linhardt RJ. Addressing endotoxin issues in bioengineered heparin. Biotechnol Appl Biochem. 2012 Nov-Dec;59(6):420-428.
- Zhao X, Yang B, Linkens K, Datta P, Onishi A, Zhang F, Linhardt RJ. Microscale separation of heparosan, heparan sulfate and heparin. Anal Biochem. 2013 Mar 15;434(2):215-7.
- Bhaskar U, Sterner E, Hickey AM, Onishi A, Zhang F, Dordick JS, Linhardt RJ. Engineering of routes to heparin and related polysaccharides. Appl Microbiol Biotechnol. 2012 Jan;93(1):1-16.
- Wang Z, Li J, Cheong S, Bhaskar U, Akihiro O, Zhang F, Dordick JS, Linhardt RJ. Response surface optimization of the heparosan N-deacetylation in producing bioengineered heparin. J Biotechnol. 2011 Dec 10;156(3):188-96.