Anne Marie Hickey
Postdoctoral Fellow and Lab Manager
Contact Info
Office: (518) 961-3138
E-mail:
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Campus Address
Room 4117 CBIS
RPI
Troy NY 12180
Biography
I moved to RPI in November 2009, from Exeter, England, where I spent the previous 4 years. Prior to that I lived and studied in Dublin, Ireland.
Education
Ph.D. Industrial Microbiology: 1999-2003. University College Dublin, Ireland.
B.Sc. Industrial Microbiology: 1995-1999. University College Dublin, Ireland.
Research
My work focuses on one main area: the NIH-funded Bioengineered Heparin Project.
Awards and Academic Honors
Society for Applied Microbiology Presidents Award, 2008
Lord Edward Fitzgerald Memorial Fund Bursary, 2001.
Research Grant from the Environmental Protection Agency (Ireland) under the Environmental Research, Technological Development and Innovation (ERTDI) Programme 2000-2006. 2001-2003
Enterprise Ireland Research Scholarship, 1999-2002
Professional Society Membership
Society for Applied Microbiology
Society for General Microbiology
Amercican Society for Microbiology
Publications
Papers
Hickey, AM, Gordon, L, Dobson, AD, Kelly, CT and Doyle, EM. 2007. Effect of surfactants on fluoranthene degradation byPseudomonas alcaligenesPA-10. Appl Microbiol Biotechnol 74, 851-856.
Hickey, AM, Marle, L, McCreedy, T,Watts, P, Greenway, GM and Littlechild, JA. 2007. Immobilization of thermophilic enzymes in miniaturized flow reactors. Biochem Soc Trans, 35, 1621–1623.
Doyle, E, Muckian, L, Hickey, AM and Clipson, N. Microbial PAH degradation. 2008. Adv Appl Microbiol, 65, 27-66.
Hickey, AM, Ngamsom, B, Wiles, C,Watts, P, Greenway, GM and Littlechild, JA. 2009. Development and use of a micro reactor for the study of biotransformations by a polymerized γ-lactamase enzyme. Biotechnology Journal, 4, 510-516.
Ngamsom, B, Hickey, AM, Greenway, GM, Littlechild, JA, Watts, P and Wiles C. Development of a high throughput screening tool for biotransformations utilising a thermophilic l-aminoacylase enzyme. 2010. J Mol Catal B-Enzym, 63, 81–86.
Ngamsom, B, Hickey, AM, Greenway, GM, Littlechild, JA, McCreedy, T, Watts, P and Wiles C. The development and evaluation of a conducting matrix for the electrochemical regeneration of the immobilised co-factor NAD(H) under continuous flow. 2010. Org Biomol Chem, 8, 2419 – 2424.
Wang, Z, Ly, M, Zhang, F, Zhong, W, Suen, A, Hickey, AM, Dordick, JS, Linhardt, RJ. E. coliK5 fermentation and the preparation of heparosan, a bioengineered heparin precursor. 2010. Biotechnology and Bioengineering,107, 964-973.
Masuko S, Higashi, K, Wang, Z, Bhaskar, U, Hickey, AM, Zhang, F, Toida, T, Dordick, JS, Linhardt, RJ. Ozonolysis of the double bond of the unsaturated uronate residue in low-molecular-weight heparin and K5 heparosan. 2011. Carbohydrate Research,346, 1962-1966.
Ladiwala, ARA, Perchiacca, JM, Fishman, ZS, Bhattacharya, M, Hickey, AM, Domigan, BG, Dordick, JS and Tessier, PM. Polyphenolic disaccharides endow proteins with unusual resistance to aggregation. Biotechnology and Bioengineering, 109, 1869-1974.
Bhaskar, U, Sterner, E, Hickey, AM, Onishi, A, Zhang, F, Dordick, JS, Linhardt, RJ. Engineering of routes to heparin and related polysaccharides. 2012. Applied Microbiology & Biotechnology 93, 1–16.
Hickey, AM, Bhaskar, U, Linhardt, RJ, Dordick, JS. 2013. Effect of Eliminase gene (elmA) Deletion on Heparosan Production and Shedding in Escherichia coli K5. Journal of Biotechnology, in press.
Patents
Hickey, AM, Wiles, C, Ngamsom, B, Watts, P, Greenway, GM and Littlechild, JA. 2010. IMMOBILIZED ENZYMES AND CO-FACTORS. WO/2010/097619.
Conference Presentations
Immobilisation and Use of Thermophilic Biocatalysts in Miniaturised Flow Reactors. Extremophiles 2008,Cape Town,South Africa. (7-11 September 2008)
Immobilisation of thermophilic enzymes in miniaturised flow reactors. Prostab 2007,Exeter,UK. (11-14 April 2007)
Effect of surfactants on xenobiotic degradation. SfAM Summer meeting 2004,Cork,Ireland. (12-14 July 2004)