Sumanth N
Jamadagni
| PhD
Candidate |
| Office: |
Biotech Building 3332 |
| Telephone: |
518-276-4278
|
| Fax: |
518-276-2207
|
| E-mail: |
jamads@rpi.edu
|
Mailing
Address: |
Dept. of Chemical
and Biological Engineering
Rensselaer Polytechnic Institute
Center for Biotechnology and Interdisciplinary Studies, Room 4211
110 8th Street
Troy, NY 12180-3590
|
| Background | Research
Area | Publications | Highlights
| Honors |
Background
B.Tech (2005), Chemical Engineering, Indian
Institute of Technology, Madras, India
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Research
area
My research in
the Dordick and
Garde groups focuses on the better understanding of enzyme behaviour in
organic
media. The goal of this work is to join experimental work and molecular
simulation to answer fundamental questions: How water molecules act on
the
surface of an enzyme to influence their activity and structural
conformation.
Will these water properties have a local or global effect on the
surface of the
enzyme? Can chemical modifications or direct mutations in the enzyme
surface
give an answer of how water influences it?
I
perform molecular dynamics simulations of
enzyme-solvent systems to answer these questions. The
results of these simulations will be used
to make predictions about hydration patterns and the effect of water on
enzymes
which can then be tested experimentally.
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Publications
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Research
Highlights
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Honors
& Awards
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|